Orthopaedic Mechanotransduction Laboratory

The Mechanotransduction Laboratory’s research focuses on understanding the role biomechanical factors play in the onset and progression of low back pain, as well as how such knowledge can be harnessed to inform treatment and improve diagnosis. Studies in the lab generally are organized into two categories:

  1. Multiscale mechanobiology - Utilizing cell biology, tissue mechanics, and mathematical models to better understand how mechanical cues are translated across multiple spatial scales, as well as to regulate cellular function in health and disease.
  2. Diagnostic biomechanics - Utilizing biomechanical measurements including magnetic resonance elastography (MRE) to improve patient identification and selection for the appropriate treatment.